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doi: 10.4155/fmc.14.86
The second pathogenic variant can be another hemoglobin S allele or other Hb variants such as HbC (HBB GLU6LYS)

Understanding Semaglutide Semaglutide is a medication that mimics the action of the GLP-1 hormone
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doi: 10.1007/s00011-020-01389-z 86 EhrenfeldMTincaniAAndreoliLCattaliniMGreenbaumAKanducDet al

Notably, these quiescent cells show heightened sensitivity to ferroptosis inducers, providing a rationale for the clinical application of arginine-restricted diets combined with ferroptosis inducers [110]