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Real-time PCR analyses were performed using SYBR Green I PCR kit (Stratagene, La Jolla, CA, USA) via Mx 3000P instrument (Stratagene)

152 Dysregulation of Wnt/-catenin signalling is often caused by mutations of various components in the pathway, particularly mutations or silencing of the Wnt tumour suppressor, which occurs frequently in various cancer types, such as adenomatous polyposis coli (APC) mutations, 193 Axin1/2 mutations, 194,195 GSK3 deletions, 196 inactivation mutations of E3 ubiquitin ligase RNF43, 196 and Znrf3

Tumour-derived PTH-related protein triggers adipose tissue browning and cancer cachexia

Osteocyte dendrites were observed using 10 m thick frozen sections prepared from femurs embedded in O.C.T

Discussion We report the discovery of the integration of two fundamental and evolutionarily conserved stress response pathways, the hypoxia response pathway and the RNA-surveillance pathway of nonsense-mediated decay

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