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A significantly greater percentage of those with higher EDSS scores experienced moderate to severe feelings of pessimism (18.7% vs 11.8%, P = .026) and lower life satisfaction (8.8% vs 3.6%, P = .016) when compared with those with stable EDSS scores

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Claudins and the modulation of tight junction permeability

PMID: 22463691 | doi:10.1146/annurev-biochem-052110-115718 Mendias CL et al

[DOI] [PubMed] [Google Scholar] 188.Tshionyi M., Shay E., Lunde E., Lin A., Han K.Y., Jain S., Chang J.H., Azar D.T

Instead, each experiment was repeated three times with different random seeds to account for stochastic variation in initialization and optimization, and the median test set performance is reported