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Unlike many digestive problems, Crohns disease can affect any part of your digestive system from your mouth to your anus though it most often affects the end of the small intestine (the ileum) and the beginning of the large intestine (the colon)

But, it doesnt necessarily mean that increased B12 levels cause weight loss

Tolerability (early human safety): Short human studies reported a placebo-like safety profile with no serious adverse events [5] [6]

[20] [21] Proton pump inhibitors (PPIs) such as omeprazole can reduce B12 absorption and may cause digestive upset

Going higher does not always mean losing faster, but it almost always means more side effects

Bile and fat which are trapped can lead to slowing down of the metabolism