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Body composition and quality of life in adults with growth hormone deficiency

[DOI] [PubMed] [Google Scholar] 611.Ischiropoulos H, Zhu L, Beckman JS

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A study in C57BL/6 mice daily treated with pQ (0.3 mg/Kg) or maneb (1 mg/Kg) or PQ + maneb from postnatal day 519 and then re-exposed as adults to PQ (10 mg/Kg) or maneb (30 mg/Kg) or PQ + maneb (twice a week/3 weeks) showed that dopaminergic cell loss and decreased dopamine levels were amplified by the adult re-challenge to the pesticides, suggesting that the developmental exposure to neurotoxins enhanced the adult susceptibility to a new toxic insult (Thiruchelvam et al., 2002)

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