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Macrophages undergo metabolic switching during differentiation into inflammatory (M1) or anti-inflammatory (M2) phenotypes

doi: 10.4088/JCP.14m09580

For optimal GH response: Morning (fasted): Mimics natural morning GH surge Post-workout: Enhances recovery and IGF-1 response Before bed: Aligns with deep sleep GH release Avoid taking it immediately after meals, as insulin blunts GH secretion

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