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bradycardia is further modulated by water temperature, extent of facial submersion, cognition (i.e., anticipation) and exercise (Ridgway et al., 1975

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Green tea comprised of compounds like epigallocatechin gallate (EGCG), which is a major catechin that inhibits VEGF secretion and receptor phosphorylation and down-regulates the outputs of matrix metalloproteinases (MMP-2 and MMP-9) and urokinase plasminogen activator (uPA), and thus impairs extracellular matrix degradation and invasion of endothelial cells [43, 143],Curcumin, a compound of Curcuma longa, inhibits angiogenesis by the inhibition of HIF-1a, VEGF, COX-2, inhibition of the NF-kB activation, and inhibition of oxidative and inflammatory responses, and commitment of endothelial sprouting and capillary formation [2, 35, 112, 352]