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Okwelogu SI, Ikechebelu JI, Agbakoba NR, Anukam KC

J.OtvosJ

2013;41:e1

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During exercise of this nature, when the use of the acetyl group via the Krebs cycle is exceeding its production by the PDC reaction, carnitine buffers against acetyl-CoA accumulation by making acetylcarnitine in an enzymatic reaction, thereby providing free Co-enzyme A to maintain the Krebs cycle flux 33

It has also been reported to ameliorate the effects of reactive oxygen species (ROS) and free radical-induced oxidative stress (OS) and minimizing pathological disorders of sperm, like adenosine triphosphate (ATP) depletion leading to insufficient axonemal phosphorylation, lipid peroxidation as well as loss of motility and viability [9, 10]