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The peptide modulates approximately 31% of human genes, upregulating pathways involved in antioxidant defense, DNA repair, and tissue remodeling while downregulating inflammatory and pro-fibrotic genes ( in vivo remains to be established in controlled human studies ( 5 Tissue repair and regeneration Aging dramatically impairs tissue repair, contributing to increased recovery time from injuries, chronic non-healing wounds, and progressive musculoskeletal decline ( 5.1 BPC-157: enhanced healing in aged and damaged tissues BPC-157, a 15-amino acid peptide derived from gastric protective proteins, promotes tissue repair through activation of angiogenic pathways (VEGFR2, Akt-eNOS, ERK1/2 signaling) essential for new blood vessel formation ( Clinical evidence remains limited

Since the 5 -reductase-1 activity is 3 to 4 times greater in malignant than in benign prostate tissues, while the 5 -reductase-2 activity is similar in these 2 diseases 91 , whether inhibition of both isozymes by combination of specific type 1 and type 2 inhibitor or using dual inhibitor is more effective in the prevention and therapy of prostate cancer is an interesting strategy and remains to be determined

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