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Bacterial overgrowth, or an imbalance of bacteria in the small intestine, can activate mast cells, leading to intestinal barrier breakdown

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However, due to the relatively small number of mast cells typically found in most tissues, phagocytosis is only a small piece of the puzzle when it comes to the role mast cells play in pathogen elimination

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S-glutathionylation of proteins and its reverse reaction deglutathionylation are both spontaneous and enzymatic