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Oxidative-induced DNA damage by ROS can cause mutations that may play a role in the development of cancer (Dizdaroglu 2012)

Resistance to platinum-based chemotherapy is a significant hurdle in the treatment of ovarian cancer, often arising from multiple cellular mechanisms

The Illumina TrueSeq Stranded mRNA Library Prep Kit was used for preparation of RNAseq libraries, followed by 100 bp PE-sequencing on an Illumina HiSeq 2500 device with a depth of 80100 million reads (4050 Mio cluster) (Illumina, Cambridge, UK)

Additionally, miR-214 significantly reduced the cell viability of GPx4-knockdown AML12 cells (Fig

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