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AHA Journals

Additionally, MSU crystals diminish intracellular NAD+ concentration by stimulating the nicotinamide adenine dinucleotide (NAD+) degrading enzyme (CD38) in macrophages, subsequently promoting IL-1 secretion (41)

doi: 10.1111/j.1439-0272.1994.tb00804.x 13 Du PlessisSSKashouAHBenjaminDJYadavSPAgarwalA

Four amino acid segments in steroid 5-reductase-1 confers insensitivity to finasteride, a competitive inhibitor

Premenstrual syndrome (PMS) and premenstrual dysphoric disorder (PMDD) also significantly impairs women's social functioning and quality of life (3437)

Furosemide causes acute and long-term hyperglycaemia and reduces glucose tolerance in mice