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Carcinogenesis 43, 217230
News 264 , 34 (1997)
This is one of the main reasons it is discussed as an alternative or adjunct to more familiar options such as NSAIDs
doi: 10.1016/j.cmet.2019.07.011 [DOI] [PMC free article] [PubMed] [Google Scholar] 354
The metabolic consequences of IDH1/2 mutations are not completely understood
While, in a separate study, Russo and colleagues showed that downregulation of Akt and IR subunit 2, an essential component of functional IR signaling, in the VTA results in reward tolerance as shown by decreased CPP behaviors over time (Russo et al., 2007)
