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The parameters assessed were: hematocrit, hemoglobin, erythrocytes, mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), MCH concentration, platelets, leucocytes, sodium, potassium creatinine, glucose, total cholesterol, aspartate aminotransferase (GOT), alkaline phosphatase, gamma-glytamyltransferase (-GT), insulin, triglycerides

The protein biomarkers include cytoplasmic aconitate hydratase (ACO1), argininosuccinate synthase (ASS1), fumarylacetoacetase (FAH), fructose-1,6-bisphosphatase 1 (FBP1) and carbamoylphosphate synthase (CPS1) ( In the past decade, using biomarkers to predict, monitor and diagnose drug-induced diseases during drug treatment or clinical trials has gradually gained wide attention among professionals ( 3.2 Predictive models for screening DILI 32% of post-approval withdrawals and 22% of clinical trial failures are caused by drug hepatotoxicity ( in vitro models for DILI risk prediction

The third major target is the selenoenzyme GPx4

F.ChircovC.GrumezescuA

By bypassing the digestive system, our IV therapy ensures that patients receive the full therapeutic benefit of these nutrients without any delays or losses

PLoS One 9 , e111200
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