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Consistent with the distribution of Firmicutes in the cecal samples, the relative abundance of Ileibacterium was highest in the WD controls (average relative abundance 68%), second highest in the LD controls (average relative abundance 51%), and lowest in the vehicle- and 5A-1MQ-treated mice switched from WD to LD (average relative abundances of 40% and 41%, respectively)

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Preservation of Lean Body Mass : Unlike traditional calorie-restriction models that can cause muscle loss, AOD-9604 research indicates a preservation of lean muscle tissue while reducing total body fat