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Although chloroplasts lack a direct counterpart in human cells-thereby limiting their one-to-one association with neurodegenerative diseases-evidence indicates that chloroplasts engage in redox-sensitive and dynamic regulatory communication with mitochondria (Stefano and Kream 2016)

The ability to measure oxidized and reduced forms of NADs and glutathiones from the same sample also minimizes effects of separate sample handling

The dose might change based on how severe the deficiency is

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