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H19 The gene encoding IGF-2 is closely co-located with that for lncRNA H19 on human chromosome 11p15

doi: 10.4103/0253-7613.106435

Processes of Bone Elongation Endochondral Ossification and Growth Plate Morphology The skeleton develops by means of two different mechanisms: (1) Intramembranous ossification, involving direct differentiation of mesenchyme cells to bone as with the development of the flat bones of the skull and (2) Endochondral ossification, occurring when mesenchyme cells condense and differentiate into cartilage tissue, which then is replaced by bone forming the vertebrae, ribs and limbs [5]

Hercynine is also known to be an intermediary precursor of the ET biosynthetic pathway in the bacterial and fungal organisms mentioned earlier