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Y.MurrayM

Deletion of glutathione biosynthesis genes in PAO1 in two separate studies have linked glutathione to the increased production of virulence factors like pyocyanin and persister cell formation, however they reported conflicting results about glutathiones effect on increasing or reducing biofilm formation (38, 39)

Nandi D, Tahiliani P, Kumar A, Chandu D

The targets for Zn-mediated impact on energy metabolism may include PPARs (proliferator-activated receptors), which are responsible for the expression of mRNA genes that play a critical role in energy metabolism [98, 99]

Although these factors are considered to be the major controls, regulation is possible at other levels, such as the availability of glycine and ATP (Buwalda et al., 1990

[DOI] [PubMed] [Google Scholar] 138.Kratz E.M., Piwowar A