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Post-translational regulation of NNMT (e.g., phosphorylation, succinylation) adds complexity and may be targeted in future therapies

I still believe it is our birthright and I will never say never

Note that human-interest senolytic dosing is usually pulsed/intermittent (a few consecutive days per cycle), so this continuous schedule diverges from the typical senolytic paradigm

One important limitation: the clinical weight loss results were modest

Disclaimer: Peptide therapies are not one-size-fits-all and may not be suitable for everyone

Australia's Therapeutic Goods Administration (TGA) added the experimental peptide BPC-157 to Schedule 4 of the Poisons Standard, the category for prescription-only medicines, with the change taking effect on June 1, 2024