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[DOI] [PMC free article] [PubMed] [Google Scholar] 114.Calapai F., Cardia L., Esposito E., Ammendolia I., Mondello C., Lo Giudice R., Gangemi S., Calapai G., Mannucci C

63,64,65 Ribose modification Ribose modifications at the 2 position have been widely used to protect siRNA from attacking ribonucleases, which require the 2-OH group for the hydrolysis of RNA

I followed all of the protocols and had a mild case but was still miserable: fever, chills, aches, terrible headache, cough and pretty terrible heart palpitations

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This prolonged exposure can lead to increased oxidative stress and cellular damage