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At the time of entering the study, all patients were off Botox except for one (#7) who used it to control epiphora and was free of any other contributary modalities that could interfere with the study

Side effects are rare but may include redness or swelling at the injection site, and occasional nausea

Further evaluation for the role of stromal cells within the tumor microenvironment in mediating resistance to anti-angiogenic drugs will improve the efficacy and durability of anti-angiogenic therapy

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ASC, adipose-derived stem cells

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