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7.4.3 GPx Studies highlight GPxs substantial role, with abundant reduced thiols, in detoxifying H 2 O 2 in CF sputum, particularly when CAT is inhibited or overwhelmed (Dauletbaev et al., 2004)

Complete blood counts, biochemical parameters, and pulmonary function test results were evaluated

116 Moreover, in a trial of 8 asthmatic patients who received nebulized GSH (600 mg with 4 ml of 0.9% sodium chloride) one week apart, adverse effects, such as bronchoconstriction, have occurred

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FIGURE 1 2.1.2 Genetic predisposition GWASs have identified multiple gout-associated genetic loci, revealing a dual-pathway urate metabolism-inflammatory regulation genetic architecture