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Identification of Five Structurally Unrelated Quorum-Sensing Inhibitors of Pseudomonas aeruginosa from a Natural-Derivative Database

Although these studies are currently in the basic research phase, some clinical trials have shown promising results

We accepted all articles written in English and we excluded book reviews, editorials, commentaries, opinion pieces, and topic overviews that did not explicitly identify as literature reviews

A study showed that Mthfr deficiency in mice exacerbated the PD-like symptoms in Mthfr +/ mice such as motor function impairments, elevated microglial activity in the substantia nigra, and increased oxidative stress in dorsal striatum suggesting that Mthfr deficiency heightens the vulnerability of substantia nigra and dorsal striatum to paraquat-induced damage [171]

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RESULTS Measurements performed at baseline of each challenge (means for 7 challenges: FEV 1 , 3.45 6 0.7 L, 92 6 10% predicted