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Ultrathin sections were obtained by using a Leica ultramicrotome (Leica Microsystems, Buffalo Grove, IL, USA) and double-stained with uranyl acetate and lead citrate (Spi-Chem, USA)

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Carey CN, Paquette M, Sahye-Pudaruth S, Dadvar A, Dinh D, Khodabandehlou K, et al

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[152] generated systemic SERAC1 knockout mice and subjected them to a high-fat diet intervention, revealing that SERAC1 deficiency elevates hepatic cholesterol while suppressing systemic cholesterol synthesis, leading to a metabolic shift favoring cholesterol production over FA synthesis

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