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If you're not on a GLP-1, lipo B12 shots are still effective on their own as part of a wellness or weight loss routine

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For example, the recommended effective cure for chronic fatigue syndrome (CFS) is a 6 to 7-milligram dose of vitamin B12 intramuscular injection per week for 3 weeks

Scientific References Frequently Asked Questions Can high vitamin B12 levels be dangerous

The test solution should be transferred with a sterile syringe to avoid external contamination

To help bypass any barriers to absorption in the GI tract, many healthcare providers recommend B12 injections for deficiency, but research shows that very high doses of oral B12 (1,000 to 2,000 mcg once a day) can normalize serum B12 levels to a similar extent with minimal side effects