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[DOI] [PMC free article] [PubMed] [Google Scholar] 20.Charache S, Grisolia S, Fiedler AJ, Hellegers AE

Notably, pharmacological blockade of opioid and benzodiazepine receptors partially reversed AST-mediated neuroprotection, suggesting that receptor-dependent mechanisms may contribute to its cognitive benefits beyond classical antioxidant activity (Rastinpour et al., 2025)

Fentanyl Fentanyl , a potent opioid analgesic, has a half-life of 2 to 4 hours and is metabolized in the liver by CYP3A4 enzymes (9)

Genomics 46, 467476

Tuli et al., 2013a)

Role of JAK2/STAT3 signaling pathway in the tumorigenesis, chemotherapy resistance, and treatment of solid tumors: A systemic review