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In these suppressors, we have identified mutations in lpdA, the gene for lipoamide dehydrogenase

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doi: 10.3390/molecules23020272

Future studies should validate these targets in preclinical models and explore their translational potential to develop interventions improving the outcomes of patients with SAE

Acknowledgements This work was supported by the Industrial Core Technology Development Program (10049112, Development of the Validation System for Efficacy Studies using Mini Pigs) funded by the Ministry of Trade, Industry & Energy (MOTIE, Korea)