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This observation is consistent with a previous report demonstrating that long-term HFD consumption impaired liver regeneration in C57BL/6 mice through suppression of NF-B activation 44

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The 24-EBR (10 8 M) was obtained by diluting a stock solution of 10 3 M in mQ water

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Discussion We provide, for the first time, direct evidence that only 38 days of extra oral glucose intakes four times a day can induce prediabetes