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Kornblau SM, Thall P, Huh YO, Estey E, Andreeff M

Pharmacogenomics Genetic polymorphisms in the drug metabolizing enzymes may be an important factor in the differential therapeutic and toxic responses in humans

Emerging evidence also points to potential epigenetic programming, in which factors such as lactoferrin and EGF (Epidermal Growth Factor) may influence the expression of key immune regulatory genes (e.g., FOXP3, IL10) and establish a long-term pathway toward immune tolerance [14]

Structure 29 , 13571370 (2021)

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