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[DOI] [PMC free article] [PubMed] [Google Scholar] 17.Xiong R., Aiken E., Caldwell R., Vernon S.D., Kozhaya L., Gunter C., Bateman L., Unutmaz D., Oh J

2019Apr 23;7(5):188897

J Inherit.Metab Dis 2006;29(2-3):288-298

Furthermore, Tak1 deficiency results in the spontaneous upregulation of ROS in these tissues even without external stimulation, indicating that TAK1 plays a crucial role in regulating cellular antioxidant levels under steady-state conditions (166)

Skin concern(s): Anti-aging, dryness, fine lines, loss of firmness / elasticity, dull skin / hyperpigmentation