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With BPC 157 therapy, given as local bath at the swollen brain, but also intraperitoneal and intragastric application, g- and ng-regimens, at 1 min, 15 min, 24 h or 48 h ligation-time, the increased (positive) pressure in the superior sagittal sinus is immediately reversed to the normal (negative) pressure

In a mouse traumatic brain injury model, prophylactic and therapeutic BPC-157 regimens were reported to reduce intensity of subarachnoidal and intraventricular hemorrhage and to attenuate consecutive brain edema (Tudor et al., 2010)

doi: 10.15252/embj.2019101964 94 LiJWangQYangYLeiCYangFLiangLet al

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