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Other causes include: pregnancy, caffeine, alcohol, or spicy food

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Gillessen, A., & Schmidt, H

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Cancer Res 78(2):489500 Hamzah J et al (2008) Vascular targeting of anti-CD40 antibodies and IL-2 into autochthonous tumors enhances immunotherapy in mice

If signs of irritation or sensitivity appear, stop use and consult a specialist
