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however, these drugs have been misused Currently available data do not suggest that rhGH treatment should be used to promote longevity Lack of GH action in mouse models is associated with extended longevity, but the mechanism underlying the increased lifespan has yet to be established Given the effects of reduced GH/IGF-1 signalling on lifespan in rodents, decreased GH action might be beneficial for humans, but clinical trials are needed to assess long-term outcome of GH/IGF-1 inhibition This is a preview of subscription content, access via your institution Access options Subscribe to this journal Receive 12 print issues and online access $189.00 per year only $15.75 per issue Buy this article Purchase on SpringerLink Instant access to the full article PDF

Pignone et al described a decreased serum melatonin and antioxidant enzymes activity in erythrocytes together with proof of increased lipid peroxidation during exacerbations in COPD and asthma [81]

The protective effect of melatonin on brain ischemia and reperfusion in rats and humans: in vivo assessment and a randomized controlled trial

Gamma-glutamyl transpeptidase

Indian J Pediatr 86:11051111 Mohanty RR, Padhy BM, Das S, Meher BR (2021) Therapeutic potential of N-acetyl cysteine (NAC) in preventing cytokine storm in COVID-19: review of current evidence