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Cells appear to be continually exposed to the threat of L-ROS-mediated destruction, as inhibition of GPX4 activity leads to the rapid accumulation of L-ROS and cell death in cell culture, and deletion of Gpx4 in mice is embryonic lethal [6, 39]

The role of distinct subcellular BDNF release sites as well as release kinetics, e.g., for cell survival or synaptic plasticity is best studied in neurons (reviewed, e.g., in Edelmann et al

Fourth, we found that the generated molecules were more structurally similar to known metabolites than molecules with identical molecular formulas sampled at random from PubChem or ChEMBL (Extended Data Fig
Reactive oxygen species as an independent marker of male factor infertility

[DOI] [PMC free article] [PubMed] [Google Scholar] 109.Paulsen CE, Carroll KS

[DOI] [PubMed] [Google Scholar] 511.Karagiannis F., Masouleh S.K., Wunderling K., Surendar J., Schmitt V., Kazakov A., Michla M., Holzel M., Thiele C., Wilhelm C
