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The cystatin C concentration begins to rise 2448 h after AKI, and this response is much faster than that of creatinine, the concentration of which increases 27 days after AKI, depending on the extent of the pre-existing kidney damage (118)

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Therefore, this article reviews the etiology, pathogenesis, clinical manifestations, and treatment options for PIH in skin of color

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Current therapies target oxidative stress through antioxidants, lifestyle modifications, and dietary changes, although the efficacy of these approaches in preventing diabetic complications is still being studied [3]

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Together these structures are referred to as the hypothalamic-pituitary-adrenal (HPA) axis [2]

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