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Impaired nitric oxide production in children with MELAS syndrome and the effect of arginine and citrulline supplementation
These authors provided evidence that leucyl aminopeptidase is the major cysteinylglycine-hydrolyzing activity in the rat liver
Peptide source quality can also vary
In rats injected with PG-PS which suffer from infiltration of inflammatory cells, synovial hyperplasia, edema, and ankle swelling, these effects of PG-PS model of arthritis can be reduced by glycine supplementation [66]
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However, since PF3845 not only induced an increase on AEA levels but also 2-AG levels (Tchantchou et al., 2014), both endocannabinoid ligands could be involved in this neuroprotective activity observed in the ipsilateral brain
