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Ergothioneine treatment protects neurons against N-methyl-D-aspartate excitotoxicity in an in vivo rat retinal model

Most patients report only mild discomfort due to the numbing cream applied before the procedure

ROS can also promote the subsequent production of superoxide or hydrogen peroxide from other enzymatic sources that are not normally ROS producers: hydrogen peroxide promotes the uncoupling of endothelial nitric oxide synthase (eNOS) to foster superoxide production rather than nitric oxide production [11, 12] and hydrogen peroxide can convert xanthine oxidoreductase to xanthine oxidase, a superoxide and hydrogen peroxide generator, either by reversible cysteine oxidation or by promoting irreversible proteolysis, [13]

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