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Description
10.1186/s12967-022-03659-2 95

The liver is one of the bodys hardest-working organs

Upon sensing the initial pro-inflammatory signal, NF-B triggers non-transcriptional or transcriptional NLRP3 inflammasome priming, leading to increased expression of the NLRP3 inflammasome pathway proteins

Metabolic fingerprints (e.g., OCR/ECAR ratio, mtDNA copy number) are emerging as key indicators for assessing resistance risk [176, 177]alongside KRAS and BRAF mutation status

Several NPs have been designed to mimic the structure and function of viral vectors called viral mimetic NPs

GSH suppression of the excess prostaglandin synthesis
