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General Precautions: Vitamin B12 deficiency that is allowed to progress for longer than 3 months may produce permanent degenerative lesions of the spinal cord

This approach helps in validating potential drug targets by confirming their interactions with drug candidates and assessing their relevance in disease mechanisms

76 GST prodrugs appear to have a more favorable adverse-event profile, given that they are ingested as an inactive compound and undergo breakdown to release cytotoxic metabolites only in the presence of high concentrations of enzymes that occur in the proximity of tumor cells, thereby reducing collateral damage to healthy cells

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(2012) Peroxiredoxins are conserved markers of circadian rhythms