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They create a cascade of events that magnify the original signal

[DOI] [PubMed] [Google Scholar] 10.Carpenter V, Matthews K, Yang SY, Goldspink G

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(2019) reveals that TDP-43 phase separation is not just a biophysical occurrence, but a central pathological mechanism in ALS and FTD, addressing the view of aggregation as a passive consequence to a dynamic and stress-induced process with functional consequences on nuclear transport and cellular survival

"Acetyl-L-carnitine physical-chemical, metabolic, and therapeutic properties: relevance for its mode of action in Alzheimer's disease and geriatric depression." Molecular Psychiatry, 5(6), 616-632.

Pendyala, Identification of novel senolytic compounds from natural food sources