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Zidovudine: A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy

Guideline 4: Specialized Dosing for Diabetic Neuropathy Diabetic patients with neuropathy can find relief with high-dose B12 therapy

Also, low bioavailability and rapid metabolism prevent the achievement of the pharmacologically relevant concentrations of the pharmacologically active compounds in preclinical studies

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Georg-Thieme-Verlag, Stuttgart 1974 Floh, L., Zimmermann, R.: GSH-induced high-amplitude swelling of mitochondria

Oxidative stress induced by viral infection is thought to disrupt the normal redox state of host cells, leading to reduced GSH stores and increased ROS production (De Flora et al., 2020)