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Indeed, researchers have reported a plethora of positive effects with different exposures of melatonin following CNS trauma, such as axonal regrowth and sprouting, conservation of a given thickness of myelin sheet in oligodendrocytes, and improved nerve maturation 96,97

Conversely, silencing GSH-synthesising enzymes (GCLC, GSS and GSR) lowered cellular GSH levels (Supplementary Figure S3A and B) and rendered the sensitive PC9 cells erlotinib-resistant (Figure 2c)

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