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Trends Food Sci Technol 104(1):6071 Valkov V, ranov H, Bilkov J, Habn M (2020) Milk thistle ( Silybum marianum ): A valuable medicinal plant with several therapeutic purposes

Trujillo-Alonso V, Pratt EC, Zong H, Lara-Martinez A, Kaittanis C, Rabie MO, Longo V, Becker MW, Roboz GJ, Grimm J, et al

& Tora, L

Dermal collagen is essential for elasticity and firmness of the skin

Although the efficacy of these drugs is significantly, but the side effects and drug resistance problems have not been solved [25]

Nagata, O