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A prospective study.Eur J Endocrinol (2004) 151(5):54955

So, for a typical 1500mcg/ml strength, a single 1ml injection costs approximately AED 20-25

The mean absolute bioavailability following intramuscular injection was approximately 14-19% in rats and 45-51% in beagle dogs, suggesting species-specific absorption characteristics relevant for dose translation to human applications

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The studies with SAR analysis also revealed that thiosemicarbazide group played a very vital role for tyrosinase inhibition, acylamino moieties crucial for enhancing the tyrosinase inhibitory activity and the acylamide substituent at 4-position on the phenyl ring increased the tyrosinase inhibitory potency

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