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Huntingtons Disease Preclinical: The role of PACAP and the PAC 1 receptor in HD is not well understood, but with post-mortem human HD hippocampal samples showing specific decreases of PAC 1 without changes in VPAC 1 or VPAC 2 , its involvement and possible therapeutic efficacy have been explored in recent years by Xifr and colleagues in R6/1 mouse models of HD

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Liu, G.-H

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