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Monocyte-derived macrophages have the ability to oxidize low-density lipoprotein (LDL) in the subendothelial region, which is harmful to arterial cell cells (Prasad and Mishra, 2022) Macrophages will consume oxidized LDL via scavenger receptors, resulting in the formation of lipid-laden foam cells (Singh et al., 2022)

The Otsu method was then applied for automatic thresholding of the I channel, followed by binarization (Convert to Mask function) to ensure a clear distinction between CMHs and surrounding tissue

Nitric Oxide System Stupnisek et al

P.HudsonG

& Goetz, F

However, we still need to overcome the following several challenges: (1) The active substances still need to be revealed in depth, and the Q-marker should be oriented towards biological effects