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Reference: DSouza S, Ryu D, Zhang L, et al
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In another study using HCT116 and SW620 colon cancer cell lines, researchers investigated the molecular mechanism underlying curcumin's anticancer activity, with a particular focus on the miR-134-5p/CDCA3/CDK1 signaling pathway (29)

[DOI] [PMC free article] [PubMed] [Google Scholar] 138.Estes C., Razavi H., Loomba R., Younossi Z., Sanyal A.J

Alshanwani AR, Mohamed AM, Faddah LM, Shaheen S, Arafah MM, Hagar H, Alhusaini AM, Alharbi FMB, AlHarthii A, Badr AM (2021) Cyanocobalamin and/or calcitriol mitigate renal damage-mediated by tamoxifen in rats: implication of caspase-3/NF-B signaling pathways

RNS are a group of reactive compounds that include NO, which is physiologically produced by NOSs, a NADPH-dependent family of enzymes present in most cells and tissues [28]
