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study in Belgium found that the rs5937843 (G/T) polymorphism in the SLC16A2 gene coding for the monocarboxylate transporter 8 (MCT8, which transports T3 and T4 specifically) was inversely associated with FT4 levels in men but not in women

Pharmaceuticals 5:802836 Musa NS, Howarth GS, Tran CD (2015) Zinc supplementation alone is effective for partial amelioration of methotrexate-induced intestinal damage

Abou Zahr A, Borthakur G

Es wird bevorzugt in der Leber gebildet, kommt aber in allen Zellen des Organismus vor, in besonders hohen Mengen (abgesehen von der Leber) in den roten Blutkrperchen und den Zellen des Immunsystems

And there are a lot of that I've seen clinically that have irr, not even irritable Crohn's colitis and they're suffering

Fujikawa T, Chuang JC, Sakata I, Ramadori G, Coppari R