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Usually present with no clinical manifestations other than cyanosis

Generally mild and reversible with dose reduction or discontinuation

This ensures the medication enters the muscle rather than subcutaneous tissue

Mechanistic and fibroblast data are robust, but large independent randomized trials comparing GHK-Cu head-to-head with tretinoin are lacking

G.CooperK

GHK-Cus ability to remodel scar tissue through its balanced MMP regulation (breaking down disorganized collagen in scars while promoting new, organized collagen formation) makes it particularly relevant for improving the appearance of stretch marks alongside loose skin