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Several clinical studies have shown a positive effect of MeD on the reduction of the risk of developing chronic metabolic diseases such as diabetes mellitus, cardiovascular diseases, arterial hypertension, but also cancer, neurodegenerative diseases and osteoporosis

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Cavernous artery flow and end-diastolic velocity were normal: peak systolic velocity was 74 cm/seconds (bilaterally)

Meesters AA, Pitassi LH, Campos V, Wolkerstorfer A, Dierickx CC

It was demonstrated in animal studies that unabsorbed quaternary amines such as choline, phosphatidylcholine, betaine or l-carnitine can be metabolized by gut microorganisms to produce the intermediate compound trimethylamine (TMA)

Biomedica 36 , 232247 (2020)